Unexplained loss of consciousness: Systemic mastocytosis
نویسندگان
چکیده
منابع مشابه
A case of unexplained episodic loss of consciousness.
T patient was a 49-year-old man with no significant past medical history, normal body mass index, and normal oral/ nasal airway anatomy, who presented with a 4-month history of episodic loss of consciousness while working as a cemetery caretaker. The patient lost consciousness while using a riding lawnmower at the cemetery during his morning landscaping duties; this caused him to lean forward i...
متن کاملIndolent systemic mastocytosis.
circular macules, less than 1 cm in diameter, located on his trunk and extremities [Figure A]. Wheals and surrounding erythema developed in the lesions after rubbing (positive Darier sign). Laboratory analyses showed mild eosinophilia with an increased total tryptase level of 40 ng/ml. Densitometry was normal. With the strong clinical suspicion of cutaneous mastocytosis, a skin biopsy was perfo...
متن کاملAnaesthetic management of systemic mastocytosis.
Systemic mastocytosis is an uncommon disorder of mast cell proliferation in connective tissues. Mast cell degranulation may occur on exposure to various stimuli and drugs. The release of histamine, heparin and vasoactive substances such as prostaglandin D2 may cause severe hypotension and other anaphylactoid manifestations. Anaesthetic management should include perioperative stabilization of ma...
متن کاملCladribine therapy for systemic mastocytosis.
Patients with systemic mastocytosis (SM) can suffer from disabling symptoms related to mast cell mediator release or mast cell infiltration, requiring mast cell eradication. In the present absence of any curative therapy, a recent case report describing the efficacy of cladribine showed promising results. In a pilot study, the efficacy of cladribine (0.10-0.13 mg/kg in a 2-hour infusion, days 1...
متن کاملFatal anaphylaxis in systemic mastocytosis.
A 42-year-old woman died after an episode of anaphylaxis associated with a raised serum histamine level. A diagnosis of systemic mastocytosis was established, with lymphadenopathy and hepatosplenomegaly, not associated with the usually pre-existing skin lesions of urticaria pigmentosa.
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ژورنال
عنوان ژورنال: Journal of the Royal Society of Medicine
سال: 2000
ISSN: 0141-0768,1758-1095
DOI: 10.1177/014107680009300309